Vietnamese scientist discovers anti-cancer agents from rice husks

Update: 17:01 | 04/11/2022

Vietnamese scientist Prof. Dr. Tran Dang Xuan and his colleagues at Hiroshima University in Japan have discovered anti-cancer agents in rice husks.

The research titled ‘Cytotoxic Mechanism of Momilactones A and B against Acute Promyelocytic Leukemia and Multiple Myeloma Cell Lines’ was published on Cancers magazine in October this year.

Vietnamese scientist, anti-cancer agents, rice husks, Prof. Dr. Tran Dang Xuan, development of Momilactone, anticancer property

Illustrative image.

This is the first study clarifying the cytotoxic mechanism of Momilactones A (MA) and Momilactones B (MB) on acute promyelocytic leukemia (APL) HL-60 and multiple myeloma (MM) U266 cell lines.

Besides, these compounds may induce G2 phase arrest in the HL-60 cell cycle through the activation of p-38 and disruption of CDK1 and cyclin B1 complex.

This finding provides novel insights into the anticancer property of Momilactones, which can be a premise for future studies and development of Momilactone-based anti-cancer medicines.

The Laboratory of Plant Physiology and Biochemistry in Hiroshimas University led by Xuan is one of the few laboratories in the world that can purify Momilactones from natural sources such as rice. In a study in 2019, the group discovered and successfully extracted 600 mg of MA and MB from 30kg of rice husks.

The scientist said many pharmaceutical companies inside and outside Japan are working with his team to extract MA and MB for developing medicines to boost the immune system, anti-cancer medicines, those for treating diabetes, and cosmetics.

Ten Vietnamese scientists listed among world’s best
Ten Vietnamese scientists working in six different fields have been ranked by the website for their achievements in scientific publications.
Association of Bac Giang scientists in Hanoi honors 17 outstanding individuals
(BGO) – The Association of Bac Giang scientists in Hanoi (Association) on August 14 held a ceremony at Hanoi Polytechnic College to honor outstanding individuals. The event was attended by Permanent Vice Chairman of Bac Giang provincial People’s Committee (PPC) Mai Son.
Indian scientists helps build capacity for Vietnam on monkeypox control
Scientists at the Indian Council of Medical Research (ICMR)’s National Institute of Virology (NIV) in Pune are training experts from Vietnam, Myanmar, Cambodia, Indonesia, Laos, Malaysia, Philippines, Sri Lanka and Thailand to tackle monkeypox amidst escalating concerns over the disease.
Scientists honoured with L’Oréal-UNESCO International Rising Talent Award
The Jury of the United Nations Educational, Scientific and Cultural Organisation (UNESCO) and the L’Oréal Foundation on June 22 presented the L’Oréal-UNESCO International Rising Talent Award in 2022 to Dr. Ho Thi Thanh Van, a chemicals scientist who is working at the Ho Chi Minh City University of Natural Resources and Environment.
Two female scientists receive Kovalevskaia Award 2021
A ceremony was held on May 16 to honour two female Vietnamese scientists with the Kovalevskaia Award 2021 for their excellent contributions to scientific research.

Source: VNA

Bình luận mới vừa được thêm vào. Click để xem
Mới nhấtHay nhấtXếp theo: